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Application in hydrogenation of pharmaceutical intermediates
Release time: 2017-10-07
Compared with Raney Ni, the activity of SRNA amorphous material hydrogenation catalyst is 1-3 times higher. And the consumption of catalysts can be reduced by 30% above.
Hydrogenation of several pharmaceutical intermediates
|
Reactants |
Reaction conditions |
Solvents |
Consumption of catalysts g /©K |
|||
|
|
|
|
SRNA |
|
||
|
Resorcinol |
< 50 |
9 |
2 |
NaOH/H2O |
50 |
100 |
|
2,5-dihydro-2,5-dimethoxy-fura |
30 |
1 |
3 |
NaOH/H2O |
25 |
70 |
|
Ofloxacin |
80 |
4 |
4 |
H2O |
300 |
500 |
|
Nitrobenzylamine |
30-50 |
7 |
4 |
C2H5OH |
90 |
200 |
|
Phenylacetonitrile |
80-120 |
8 |
3 |
-- |
70 |
100 |
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